Publikationen
1
Originalarbeiten
1
Reviews
1
Buchartikel
1
Patente
Originalarbeiten

1. Oehmcke-Hecht S, Berlin P, Müller-Hilke B, Kreikemeyer B, Vasudevan P, Henze L, Khaimov V, Vollmar B, David R, Maletzki C. The versatile role of the contact system in cardiovascular disease, inflammation, sepsis and cancer. Biomed Pharmacother. 2021 Nov 18;145:112429. doi: 10.1016/j.biopha.2021.112429. Online ahead of print.

Impact Factor: 6.529

2. Bej S., Galow A.-M., David R., Wolfien M., Wolkenhauer O. Automated annotation of rare-cell types from single-cell RNA-sequencing data through synthetic oversampling. BMC Bioinformatics 22, 557 (2021). https://doi.org/10.1186/s12859-021-04469-x 

Impact Factor: 3.169

3. Galow A.-M., Kussauer S, Wolfien M, Brunner RM, Goldammer T, David R, Hoeflich A. Quality control in scRNA-Seq can discriminate pacemaker cells: the mtRNA bias. Cell. Mol. Life Sci. (2021). https://doi.org/10.1007/s00018-021-03916-5

Impact Factor: 9.261

4. Marquardt S, Pavlopoulou A, Takan I, Dhar P, Pützer BM, Logotheti S. A systems-based key innovation-driven approach infers co-option of jaw developmental programs during cancer progression. Front Cell Dev Biol. 2021; 9:682619. doi:10.3389/fcell.2021.682619. eCollection 2021.

Impact Factor: 5.201

5. Zhang Y, Otto P, Qin L, Eiber N, Hashemolhosseini S, Kröger S, Brinkmeier H (2021). Methocarbamol blocks muscular Na(v) 1.4 channels and decreases isometric force of mouse muscles. Muscle Nerve. 2021 Jan;63(1):141-150.   doi: 10.1002/mus.27087

Impact Factor: 2.505

6. Johann L, Chabanovska O, Lang CI, David R, Lemcke H (2020). Analyzing the α-Actinin Network in Human iPSC-Derived Cardiomyocytes Using Single Molecule Localization Microscopy. J Vis Exp. 2020 Nov 3;(165). doi: 10.3791/61605

Impact Factor: 1.3

7. Logotheti S, Marquardt S, Richter C, Hain RS, Murr N, Takan I, Pavlopoulou A, Pützer BM. Neural networks recapitulation by cancer cells promotes disease progression: a novel role of p73 isoforms in cancer‐neuronal crosstalk. Cancers 2020; 12(12):3789. Special Issue “Stemness and Differentiation in Cancer” DOI: 3390/cancers12123789

Impact Factor: 6.126

8. Klinder A, Kussauer S, Hiemer B, Wree A, Bader R, Jonitz-Heinke A (2020). Influence of Conditioned Media on the Re-Differentiation Capacity of Human Chondrocytes in 3D Spheroid Cultures. August 2020. Journal of Clinical Medicine. doi:10.3390/jcm9092798

Impact Factor: 3.303

9. Vasudevan P, Wolfien M, Lemcke H, Lang CI, Skorska A, Gaebel R, Koczan D, Lindner T, Engelmann R, Vollmar B, KrauseBJ, Wolkenhauer O, Lang H, Steinhoff G, David R (2020). Cardiomyocyte Transplantation after Myocardial Infarction Alters the Immune Response in the Heart. Cells. 2020 Aug 3;9(8):1825. doi: 10.3390/cells9081825

Impact Factor: 6.6

10. Logotheti S*, Marquardt S*, Shailendra K Gupta*, Richter C*, Edelhäuser BAH, Engelmann D, Brenmoehl J, Söhnchen C, Murr N, Alpers M, Singh KP, Wolkenhauer O, Heckl D, Spitschak A, Pützer BM. LncRNA‐SLC16A1‐ AS1 induces metabolic reprogramming during bladder cancer progression as target and co‐activator of E2F1. Theranostics 2020; 10(21):9620‐9643. (*equal contribution). DOI: 7150/thno.44176

Impact Factor: 8.579

11. Zarniko N., Skorska A., Steinhoff G., David R., Gaebel R. Dose-Independent Therapeutic Benefit of Bone Marrow Stem Cell Transplantation after MI in Mice. Biomedicines. 2020 Jun 11;8(6):E157. doi: 10.3390/biomedicines8060157

Impact Factor: 4.717

12. Lang C.I., Döring P., Gäbel R., Vasudevan P., Lemcke H., Müller P.,  Stenzel J., Lindner T., Joksch M., Kurth J., Bergner C., Wester H.-J.,  Ince H.,  Steinhoff G., Vollmar B., David R., Krause B. J.  [ 68 Ga]-NODAGA-RGD Positron Emission Tomography (PET) for Assessment of Post Myocardial Infarction Angiogenesis as a Predictor for Left Ventricular Remodeling in Mice After Cardiac Stem Cell Therapy. Cells. 2020 May 30;9(6):E1358. doi: 10.3390/cells9061358.

Impact Factor: 6.6

13. Galow A.-M., Wolfien M., Müller P., Bartsch M., Brunner R. M., Hoeflich A., Wolkenhauer O., David R., Goldammer T.Integrative Cluster Analysis of Whole Hearts Reveals Proliferative Cardiomyocytes in Adult Mice. Cells. 2020 May; 9(5): 1144. doi: 10.3390/cells9051144

Impact Factor: 6.6

14. Vasudevan P., Gäbel R., Stenzel J., Förster J., Kurth J., Vollmar B., Krause B. J., Ince H., David R., Lang C.I. 18 F-FDG PET-Based Imaging of Myocardial Inflammation Following Acute Myocardial Infarction in a Mouse Model. Int J Mol Sci. 2020 May 8;21(9):3340. doi: 10.3390/ijms21093340.

Impact Factor: 4.183

15. Lemcke H., Skorska A., Lang C.I. , Johann L., David R. Quantitative Evaluation of the Sarcomere Network of Human hiPSC-Derived Cardiomyocytes Using Single-Molecule Localization Microscopy. Int J Mol Sci. 2020 Apr 17;21(8):2819. doi: 10.3390/ijms21082819.

Impact Factor: 4.183

16. Uellendahl-Werth F, Wolfien M, Franke A, Wolkenhauer O, Ellinghaus D. A benchmark of hemoglobin blocking during library preparation for mRNA-Sequencing of human blood samples​.  Sci Rep. 2020 Mar 27;10(1):5630.  doi: 10.1038/s41598-020-62637-0

Impact Factor: 4.011

17. Wolfien M, Galow AM, Müller P, Bartsch M, Brunner RM, Goldammer T, Wolkenhauer O, Hoeflich A, David R. Single Nuclei Sequencing of entire Mammalian Hearts: Strain-dependent Cell Type Composition and Velocity. Cardiovasc Res. 2020 Jun 1;116(7):1249-1251. doi: 10.1093/cvr/cvaa054

Impact Factor: 10.787

18. Mueller P, Wolfien M, Ekat K, Lang CI, Koczan D, Wolkenhauer O, Hahn O, Peters K, Lang H, David R, Lemcke H. RNA-Based Strategies for Cardiac Reprogramming of Human Mesenchymal Stromal Cells. Cells. 2020 Feb; 9(2): 504. Published online 2020 Feb 22. doi: 10.3390/cells9020504

Impact Factor: 6.6

19. Wolfien M, Galow AM, Müller P, Bartsch M, Brunner RM, Goldammer T, Wolkenhauer O, Hoeflich A, David R. Single Nuclei Sequencing of an entire Mammalian Heart: Cell Type Composition and Velocity. Cells.  2020 Feb; 9(2): 318. doi: 10.3390/cells9020318

Impact Factor: 6.6

20. Vasudevan P., Gaebel R., Doering P., Mueller P., Lemcke H., Stenzel J., Lindner T., Kurth J., Steinhoff G., Vollmar B., Krause B.J., Ince H., David R., Lang C.I. (2019) 18F-FDG PET-Based Imaging of Myocardial Inflammation Predicts a Functional Outcome Following Transplantation of mESC-Derived Cardiac Induced Cells in a Mouse Model of Myocardial Infarction. Cells. 2019 Dec 11;8(12). pii: E1613. doi: 10.3390/cells8121613.

Impact Factor: 6.6

21. Thiele F., Voelkner C., Krebs V., Müller P., Jung J.J., Rimmbach C., Steinhoff G., Noack T., David R., Lemcke H. (2019) Nkx2.5 Based Ventricular Programming of Murine ESC-Derived Cardiomyocytes. Cell Physiol Biochem. 2019; 53(2):337-354. doi: 10.33594/000000142.

Impact Factor: 5.5

Reviews

1. A. Galow, S. Peleg.  How to Slow down the Ticking Clock: Age-Associated Epigenetic Alterations and Related Interventions to Extend Life Span. Cells 2022, 11, 468.  https://doi.org/10.3390/cells11030468

 

Impact Factor: 6.6

2. Salybekov, A.A., Wolfien, M.,  Kobayashi, S., Steinhoff, G., Asahara, T. Personalized Cell Therapy for Patients with Peripheral Arterial Diseases in the Context of Genetic Alterations: Artificial Intelligence-Based Responder and Non-Responder Prediction. Cells 2021, 10, 3266. https://doi.org/10.3390/cells10123266

Impact Factor: 6.6

3. Chabanovska O, Galow A-M, David R,  Lemcke H. (2021). mRNA – a Game Changer in Regenerative Medicine, Cell-based Therapy and Reprogramming Strategies. Adv Drug Deliv Rev. 2021 Oct 12;114002. doi:  10.1016/j.addr.2021.114002. Online ahead of print.

Impact Factor: 15.470

4. Hornschuh M, Wirthgen E, Wolfien M, Singh KP, Wolkenhauer ODäbritz J (2021). The role of epigenetic modifications for the pathogenesis of Crohn’s disease. Clin Epigenetics. 2021 May 12;13(1):108. doi:10.1186/s13148-021-01089-3

Impact Factor: 5.028

5. Galow A, Goldammer T and Hoeflich A (2020). Xenogeneic and Stem Cell-Based Therapy for Cardiovascular Diseases: Genetic Engineering of Porcine Cells and Their Applications in Heart Regeneration. Int J Mol Sci. 2020; 21(24):9686. doi: 10.3390/ijms21249686

Impact Factor: 4.556

6. Müller-Ruch U, Skorska A, Lemcke H, Steinhoff G, David R. (2020). GLP: A Requirement in Cell Therapies – Perspectives for the Cardiovascular Field. Adv Drug Deliv Rev . 2020 Apr 16;S0169-409X(20)30023-5.  doi: 10.1016/j.addr.2020.04.003. Online ahead of print.

Impact Factor: 15.470

7. Kussauer S., David R., Lemcke H. (2019) hiPSCs Derived Cardiac Cells for Drug and Toxicity Screening and Disease Modeling: What Micro- Electrode-Array Analyses Can Tell Us. Cells. 2019 Oct 28;8(11). pii: E1331. doi: 10.3390/cells8111331

Impact Factor: 5.656

Buchartikel

1. Wolfien M, David R, Galow AM (2021). Single-Cell RNA Sequencing Procedures and Data Analysis. In: Helder I. N, editor. Bioinformatics [Internet]. Brisbane (AU): Exon Publications; 2021 Mar 20. Chapter 2. doi: https://doi.org/10.36255/exonpublications.bioinformatics.2021.ch2

2. Wolfien M, Brauer DL, Bagnacani A, Wolkenhauer O (2019). Workflow Development for the Functional Characterization of ncRNAs. Springer, chapter in Computational Biology of Non-Coding RNA. Methods in Molecular Biology, vol 1912. doi: 10.1007/978-1-4939-8982-9_5

Patente

Verfahren zur Überwachung des Verlaufs einer Kardiomyozyten Transplantation und Methode zur Bestimmung, ob ein Proband für einer Kardiomyozyten Transplantation geeignet ist

Praveen Vasudevan, Markus Wolfien, Robert David

Germany: granted in April 2021
Deutsches Patent- und Markenamt, Aktenzeichen: 102020205364

Method for producing sinoatrial node cells (Pacemaker cells) from stem cells, and use of the produced sinoatrial node cells

Germany: granted in 2013.

Worldwide: granted in 2014 (JP, EP (AT, CH, FR, GB, NL, SE)), pending (CA, CN, IN, KP, US).